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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
STX12
All Species:
10.91
Human Site:
Y242
Identified Species:
18.46
UniProt:
Q86Y82
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86Y82
NP_803173.1
276
31642
Y242
E
Q
L
Q
R
A
A
Y
Y
Q
K
K
S
R
K
Chimpanzee
Pan troglodytes
XP_001150085
279
31957
Y245
E
Q
L
Q
R
A
A
Y
Y
Q
K
K
S
R
K
Rhesus Macaque
Macaca mulatta
XP_001112101
276
31639
Y242
E
Q
L
Q
R
A
A
Y
Y
Q
K
K
S
R
K
Dog
Lupus familis
XP_535342
274
31382
D235
V
H
V
E
R
A
T
D
Q
L
Q
R
A
A
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER00
274
31177
D235
V
H
V
E
R
A
T
D
Q
L
Q
R
A
A
Y
Rat
Rattus norvegicus
O70257
261
29832
R226
Q
A
N
Q
Q
L
S
R
A
A
N
Y
Q
R
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518833
249
28356
A216
S
D
Q
L
Q
R
A
A
H
Y
Q
K
K
S
R
Chicken
Gallus gallus
XP_001232002
272
30779
E233
V
H
V
E
R
A
S
E
Q
L
Q
R
A
A
Y
Frog
Xenopus laevis
NP_001079671
259
29246
A226
N
Q
Q
L
A
T
A
A
E
Y
Q
R
K
S
R
Zebra Danio
Brachydanio rerio
XP_697581
267
30970
E228
V
H
V
E
R
G
A
E
Q
L
Q
H
A
A
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24547
291
33630
Q252
D
Y
V
Q
T
A
T
Q
D
T
K
K
A
L
K
Honey Bee
Apis mellifera
XP_396269
271
30684
S232
V
S
V
N
E
A
T
S
H
V
R
Q
A
S
I
Nematode Worm
Caenorhab. elegans
O16000
291
33234
Q257
A
D
T
K
K
A
V
Q
Y
Q
S
K
A
R
R
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39233
279
31043
V243
A
A
T
T
Q
A
T
V
Q
L
R
K
A
A
K
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.5
94.9
N.A.
92.3
51.8
N.A.
77.5
84.4
50.7
65.2
N.A.
20.6
42.3
23.3
N.A.
Protein Similarity:
100
98.9
99.6
97
N.A.
96.7
70.2
N.A.
86.2
91.6
70.6
81.5
N.A.
41.2
67.7
42.6
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
13.3
20
N.A.
13.3
13.3
13.3
13.3
N.A.
33.3
6.6
33.3
N.A.
P-Site Similarity:
100
100
100
46.6
N.A.
46.6
40
N.A.
40
53.3
33.3
40
N.A.
53.3
40
60
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
30.1
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
53.4
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
15
0
0
8
72
43
15
8
8
0
0
58
36
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
0
0
0
0
15
8
0
0
0
0
0
0
% D
% Glu:
22
0
0
29
8
0
0
15
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% G
% His:
0
29
0
0
0
0
0
0
15
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% I
% Lys:
0
0
0
8
8
0
0
0
0
0
29
50
15
0
43
% K
% Leu:
0
0
22
15
0
8
0
0
0
36
0
0
0
8
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
8
8
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
29
15
36
22
0
0
15
36
29
43
8
8
0
0
% Q
% Arg:
0
0
0
0
50
8
0
8
0
0
15
29
0
36
22
% R
% Ser:
8
8
0
0
0
0
15
8
0
0
8
0
22
22
0
% S
% Thr:
0
0
15
8
8
8
36
0
0
8
0
0
0
0
0
% T
% Val:
36
0
43
0
0
0
8
8
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
22
29
15
0
8
0
0
29
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _